Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381667 | 0.89 | MAOB (0.46) | MAPTCA2MAOAMAOBCA1 | |
| Phosphoric Acid SCHEMBL8773256 | 0.83 | MAOB (0.48) | MAPTMAOBHSD17B1HSD17B2 | |
| SCHEMBL8773248 | 0.81 | MAPT (0.41) | MAPTCA2 | |
| SCHEMBL8031606 | 0.79 | MAPT (0.43) | MAPTCA2 | |
| SCHEMBL8773250 | 0.79 | CA2 (0.50) | MAPTCA2MAOAMAOBHSD17B1 | |
| SCHEMBL3086399 | 0.75 | MAPT (0.61) | MAPTMAOAMAOBHSD17B1HSD17B2 | |
| SCHEMBL4638895 | 0.74 | KMT2A (0.64) | MAPTCA2PPARACA1CA4 | |
| SCHEMBL3086757 | 0.72 | NPC1 (0.63) | MAPTCA2CA1HSD17B1HSD17B2 | |
| SCHEMBL11058650 | 0.71 | CA2 (0.68) | CA2CA1CA4 | |
| Phosphoric Acid SCHEMBL8381672 | 0.70 | HSD17B1 (0.57) | MAPTCA2MAOBCA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424465-B1 | PREPARATION AND USE OF FLUORESCENT BENZOTHIAZOLE DERIVATIVES | JBL SCIENT INC (US) | 1997-10-29 | — | — | EP | disclosed |
| US-5424440-A | A non-fluorescent detector when hydrolyzing with selected enzyme become fluorescent; colorimetric analysis, spectrophotometry | JBL SCIENTIFIC, INC. (US) | 1995-06-13 | — | — | US | disclosed |