Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424409 | 0.91 | MEN1 (0.45) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL7044546 | 0.87 | MEN1 (0.42) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL4433517 | 0.85 | MEN1 (0.41) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL4421172 | 0.85 | GBA1 (0.44) | MEN1KMT2AGAATP53S1PR1 | |
| SCHEMBL9617015 | 0.83 | GBA1 (0.47) | GNAI3GNAO1GNAI1GAATP53 | |
| SCHEMBL9769271 | 0.83 | GBA1 (0.47) | GNAI3GNAO1GNAI1GAATP53 | |
| SCHEMBL9769185 | 0.83 | GBA1 (0.47) | GNAI3GNAO1GNAI1GAATP53 | |
| SCHEMBL10416554 | 0.83 | MEN1 (0.42) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL9633873 | 0.83 | MEN1 (0.42) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL31093212 | 0.83 | GBA1 (0.47) | GNAI3GNAO1GNAI1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670316-B1 | 1,3,6-Trialkylhexahydro-1,3,6-triazocine-2-one and preparation process thereof | MITSUI TOATSU CHEMICALS (JP) | 1997-09-03 | — | — | EP | disclosed |
| US-5514793-A | 1,3,6-trialkylhexahydro-1,3,6-triazocine-2-on and preparation process thereof | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0670316-A1 | 1,3,6-Trialkylhexahydro-1,3,6-triazocine-2-one and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-09-06 | — | — | EP | disclosed |