Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | RGS4 | P49798 | 2/20 | 0.35 |
| ▸ | RGS8 | P57771 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633873 | 0.95 | MEN1 (0.42) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL4424409 | 0.91 | MEN1 (0.45) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL24822290 | 0.90 | PER2 (0.39) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL4602079 | 0.90 | ALOX5 (0.46) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL427150 | 0.90 | ALOX5 (0.46) | MEN1KMT2AGAAALOX5L3MBTL1 | |
| SCHEMBL14917572 | 0.89 | ALOX5 (0.44) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL17836960 | 0.87 | ALOX5 (0.47) | GAATP53ALOX5ALDH1A1HPGD | |
| SCHEMBL7044546 | 0.86 | MEN1 (0.42) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL10582154 | 0.86 | DPP4 (0.38) | MEN1KMT2AGAATP53DPP4 | |
| SCHEMBL10416569 | 0.86 | FKBP1A (0.41) | MEN1KMT2AGAATP53ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918186-A | Process for producing cyclic ureas | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-04-17 | — | — | US | disclosed |
| US-4900820-A | REACTING UREA WITH ACYCLIC DIAMINE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-02-13 | — | — | US | disclosed |
| EP-0249136-A2 | Process for producing cyclic ureas | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-12-16 | — | — | EP | disclosed |
| EP-0248220-A2 | Process for producing cyclic ureas | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-12-09 | — | — | EP | disclosed |