Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773370 | 1.00 | FURIN (0.43) | FURINIDO1LRRK2ALDH1A1LMNA | |
| SCHEMBL10481663 | 0.82 | BCHE (0.47) | IDO1LRRK2ALDH1A1LMNAPOLB | |
| SCHEMBL18786507 | 0.76 | ALDH1A1 (0.45) | IDO1LRRK2ALDH1A1LMNAPOLB | |
| SCHEMBL27597926 | 0.73 | ALDH1A1 (0.41) | IDO1LRRK2ALDH1A1LMNAPOLB | |
| SCHEMBL30895613 | 0.73 | L3MBTL1 (0.46) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL8151933 | 0.73 | L3MBTL1 (0.46) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL3610496 | 0.73 | L3MBTL1 (0.46) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL3610499 | 0.73 | L3MBTL1 (0.46) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL14806769 | 0.70 | ALDH1A1 (0.79) | IDO1LRRK2ALDH1A1LMNAPOLB | |
| SCHEMBL19713080 | 0.70 | L3MBTL1 (0.56) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639587-B1 | Diene polymers and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE FIRESTONE INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0510410-B1 | Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine | BRIDGESTONE FIRESTONE INC (US) | 1996-06-12 | — | — | EP | disclosed |
| EP-0639587-A1 | Diene polymeres and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE/FIRESTONE, INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0451604-B1 | Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines | BRIDGESTONE FIRESTONE INC (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5310798-A | Tire treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5227431-A | DIENE POLYMERS AND COPOLYMERS JUMPED BY PARTIAL CROSSLINKING AND TERMINATED WITH A SUBSTITUTED IMINE | BRIDGESTONE/FIRESTONE, INC. (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0510410-A1 | Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5109907-A | Tire treads with reduced rolling resistance | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-05-05 | — | — | US | disclosed |
| US-5066729-A | Tire Treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0451604-A2 | Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | disclosed |