Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746684 | 1.00 | HDAC6 (0.41) | HDAC6TSHRKCNH2ALDH1A1TP53 | |
| SCHEMBL8746679 | 0.93 | TSHR (0.42) | HDAC6TSHRKCNH2ALDH1A1GRM2 | |
| SCHEMBL20157017 | 0.90 | TSHR (0.40) | HDAC6TSHRALDH1A1L3MBTL1NPC1 | |
| SCHEMBL20133582 | 0.86 | TSHR (0.42) | HDAC6TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL3477012 | 0.82 | TSHR (0.39) | HDAC6TSHRKCNH2ALDH1A1TP53 | |
| SCHEMBL9798892 | 0.82 | KCNH2 (0.47) | KCNH2ALDH1A1TP53NPC1JAK2 | |
| SCHEMBL27687752 | 0.82 | HDAC6 (0.34) | HDAC6TSHRKCNH2 | |
| SCHEMBL9278064 | 0.80 | KCNH2 (0.44) | KCNH2ALDH1A1TP53NPC1JAK2 | |
| SCHEMBL16583810 | 0.78 | KDM4E (0.41) | TSHRALDH1A1L3MBTL1HSD17B10HPGD | |
| SCHEMBL2560142 | 0.78 | TSHR (0.45) | HDAC6TSHRALDH1A1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639587-B1 | Diene polymers and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE FIRESTONE INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0543305-B1 | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from fused-ring polynuclear aromatic compounds or aromatic nitrile compounds | BRIDGESTONE CORP (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0639587-A1 | Diene polymeres and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE/FIRESTONE, INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5310798-A | Tire treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5254628-A | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from aromatic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0543305-A1 | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from fused-ring polynuclear aromatic compounds or aromatic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 1993-05-26 | — | — | EP | disclosed |