Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157017 | 0.93 | TSHR (0.40) | TSHRMAPTSMN1; SMN2ARALDH1A1 | |
| SCHEMBL8746679 | 0.89 | TSHR (0.42) | TSHRMAPTSMN1; SMN2ARALDH1A1 | |
| SCHEMBL8773387 | 0.86 | HDAC6 (0.41) | TSHRALDH1A1HDAC6NPC1RAB9A | |
| SCHEMBL8746684 | 0.86 | HDAC6 (0.41) | TSHRALDH1A1HDAC6NPC1RAB9A | |
| SCHEMBL2560142 | 0.84 | TSHR (0.45) | TSHRMAPTALDH1A1HTTHDAC6 | |
| SCHEMBL1344312 | 0.81 | ALDH1A1 (0.41) | TSHRMAPTALDH1A1HTTHDAC6 | |
| SCHEMBL8538280 | 0.81 | TSHR (0.38) | TSHRMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL20149791 | 0.81 | CRHR1 (0.34) | ALDH1A1CRHR1ALDH3A1ALDH1A3 | |
| SCHEMBL5167326 | 0.81 | HTR1A (0.37) | ALDH1A1CRHR1ALDH3A1ALDH1A3 | |
| SCHEMBL11160454 | 0.79 | TSHR (0.37) | TSHRMAPTALDH1A1HTTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | TSHR 4664/4885MAPT 1388/4885SMN1; SMN2 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.