Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 7/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzonitrile SCHEMBL8746686 | 1.00 | SIGMAR1 (0.56) | SIGMAR1TSHRMGLLHSD17B10ALDH1A1 | |
| Benzonitrile SCHEMBL8746681 | 0.93 | TSHR (0.54) | SIGMAR1TSHRMGLLHSD17B10ALDH1A1 | |
| Benzonitrile SCHEMBL11429781 | 0.87 | EPHX1 (0.56) | SIGMAR1TSHRMGLLHSD17B10ALDH1A1 | |
| Benzonitrile SCHEMBL27895198 | 0.87 | TSHR (0.67) | TSHRMGLLHSD17B10ALDH1A1 | |
| SCHEMBL11642729 | 0.82 | TBXA2R (0.45) | SIGMAR1TSHRMGLLHSD17B10ALDH1A1 | |
| Phenylacetylene SCHEMBL2832826 | 0.82 | SIGMAR1 (0.56) | SIGMAR1TSHRALDH1A1CHRM2NAAA | |
| Benzonitrile SCHEMBL11786906 | 0.81 | ADH1B (0.55) | SIGMAR1TSHRMGLLHSD17B10NAAA | |
| Benzonitrile SCHEMBL28758173 | 0.80 | TSHR (0.52) | TSHRMGLLHSD17B10ALDH1A1NAAA | |
| Biphenyl SCHEMBL22832517 | 0.79 | SIGMAR1 (0.66) | SIGMAR1TSHRALDH1A1CHRM2NAAA | |
| Biphenyl SCHEMBL5716029 | 0.79 | SIGMAR1 (0.66) | SIGMAR1TSHRALDH1A1CHRM2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639587-B1 | Diene polymers and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE FIRESTONE INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0543305-B1 | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from fused-ring polynuclear aromatic compounds or aromatic nitrile compounds | BRIDGESTONE CORP (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0639587-A1 | Diene polymeres and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE/FIRESTONE, INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5310798-A | Tire treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5254628-A | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from aromatic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0543305-A1 | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from fused-ring polynuclear aromatic compounds or aromatic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 1993-05-26 | — | — | EP | disclosed |