Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4155499 | 0.83 | PLK1 (0.53) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30339452 | 0.83 | PLK1 (0.53) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8773443 | 0.83 | HPGD (0.62) | NPC1RAB9AHDAC8MPOHIF1A | |
| SCHEMBL4815209 | 0.83 | HPGD (0.62) | NPC1RAB9AHDAC8MPOHIF1A | |
| SCHEMBL28610687 | 0.82 | HDAC8 (0.48) | NPC1RAB9AHDAC8MPOHIF1A | |
| SCHEMBL668153 | 0.82 | P2RX7 (0.53) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9493594 | 0.82 | ALDH1A1 (0.62) | NPC1RAB9AHDAC8MPOHIF1A | |
| SCHEMBL6444002 | 0.82 | NPC1 (0.50) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7757783 | 0.81 | HDAC6 (0.44) | HDAC8MPOHIF1AGAAKDM4E | |
| SCHEMBL9736935 | 0.81 | PTGS2 (0.71) | NPC1RAB9AHDAC8MPOHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461010-A2 | HYDROXAMIC ACID AND ITS DERIVATIVES AS INHIBITORS OF MELANOCYTE TYROSINASE FOR TOPICAL SKIN LIGHTENERS | Integriderm, Inc. (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6632833-B1 | Their preparation and to their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-14 | — | — | US | disclosed |
| WO-2003057184-A2 | HYDROXAMIC ACID AND ITS DERIVATIVES AS INHIBITORS OF MELANOCYTE TYROSINASE FOR TOPICAL SKIN LIGHTENERS | INTEGRIDERM, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| EP-0942901-A1 | CYCLIC IMINES AS PESTICIDES | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022438-A1 | CYCLIC IMINES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-28 | — | — | WO | disclosed |