Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2884029 | 0.87 | CRHBP (0.53) | CRHBPCRHR2TDP1PTPN1CYP2C19 | |
| SCHEMBL31206998 | 0.83 | CRHBP (0.49) | CRHBPCRHR2TDP1PTPN1CYP2C19 | |
| SCHEMBL13322100 | 0.78 | CYP2C19 (0.47) | CRHBPCRHR2TDP1PTPN1CYP2C19 | |
| SCHEMBL28813822 | 0.78 | CRHBP (0.53) | CRHBPCRHR2TDP1PTPN1CYP2C19 | |
| SCHEMBL2887865 | 0.77 | CRHBP (0.49) | CRHBPCRHR2TDP1PTPN1CYP2C19 | |
| SCHEMBL28458480 | 0.76 | PTPN1 (0.65) | CRHBPCRHR2TDP1PTPN1CYP2C19 | |
| SCHEMBL14510437 | 0.76 | TSHR (0.50) | CRHBPCRHR2PTPN1CYP2C19NR1H2 | |
| SCHEMBL12346186 | 0.75 | CYP2C19 (0.56) | CRHBPCRHR2PTPN1CYP2C19NR1H2 | |
| SCHEMBL6009444 | 0.75 | CRHBP (0.47) | CRHBPCRHR2TDP1PTPN1NR3C1 | |
| SCHEMBL6009438 | 0.75 | CRHBP (0.47) | CRHBPCRHR2TDP1PTPN1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647217-B1 | 4-ACYLAMINOBENZAMIDES AND THEIR USE AS FUNGICIDES | ZENECA LTD (GB) | 1997-10-29 | — | — | EP | disclosed |
| EP-0647217-A1 | 4-ACYLAMINOBENZAMIDES AND THEIR USE AS FUNGICIDES. | ZENECA LTD (GB) | 1995-04-12 | — | — | EP | disclosed |
| WO-1994000422-A2 | 4-ACYLAMINOBENZAMIDES AND THEIR USE AS FUNGICIDES | ZENECA LIMITED (GB) | 1994-01-06 | — | — | WO | disclosed |