Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 9/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028575 | 0.71 | ITGB1 (0.42) | MAPT | |
| SCHEMBL7772078 | 0.71 | ITGB1 (0.42) | MAPT | |
| SCHEMBL9835699 | 0.71 | ALDH1A1 (0.32) | NPC1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9835693 | 0.71 | ALDH1A1 (0.32) | NPC1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11177371 | 0.67 | CHRNA7 (0.37) | BRD4CREBBPEP300GAAALDH1A1 | |
| SCHEMBL8642950 | 0.66 | — | — | |
| SCHEMBL9836002 | 0.66 | — | — | |
| SCHEMBL5664608 | 0.66 | ALDH1A1 (0.46) | L3MBTL1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8772405 | 0.65 | EPHX1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29084651 | 0.65 | SLC6A2 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582291-B1 | Process for preparing carbapenem derivatives | TANABE SEIYAKU CO (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5359059-A | Cyclization of azetidinone compound with base and silylating agent | TANABE SEIYAKU CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0582291-A1 | Process for preparing carbapenem derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1994-02-09 | — | — | EP | disclosed |