Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPRB | P23467 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773558 | 0.84 | APP (0.64) | MAOBPTPN1PTPRCPTPN2PTPRB | |
| SCHEMBL4883457 | 0.80 | MAOB (0.72) | MAOBPTPN1PTPRCPTPN2PTPRB | |
| SCHEMBL8773537 | 0.78 | PTPN1 (0.52) | MAOBPTPN1PTPRCPTPN2PTPRB | |
| SCHEMBL5511955 | 0.78 | MAOB (0.70) | MAOBPTPN1PTPRCPTPN2PTPRB | |
| SCHEMBL508697 | 0.78 | MAOB (0.70) | MAOBPTPN1PTPRCPTPN2PTPRB | |
| SCHEMBL23266730 | 0.78 | MAOB (0.70) | MAOBPTPN1PTPRCPTPN2PTPRB | |
| SCHEMBL4339843 | 0.78 | MAOB (1.00) | MAOBPTPN1PTPRCPTPN2PTPRB | |
| SCHEMBL21568941 | 0.78 | MAOB (0.70) | MAOBPTPN1PTPRCPTPN2PTPRB | |
| SCHEMBL18164548 | 0.78 | MAOB (0.70) | MAOBPTPN1PTPRCPTPN2PTPRB | |
| SCHEMBL6333407 | 0.78 | MAOB (0.70) | MAOBPTPN1PTPRCPTPN2PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577555-B1 | Derivatives of carboxylic acids | CIBA GEIGY AG (CH) | 1997-11-05 | — | — | EP | claimed |