Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPRB | P23467 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRG | P48443 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773563 | 0.85 | RXRA (0.46) | PTPN1PTPRCPTPN2PTPRBPTPN6 | |
| SCHEMBL8773573 | 0.80 | HTR1A (0.48) | MAOBRXRARXRBRXRGLIPE | |
| SCHEMBL30889094 | 0.80 | APP (0.63) | PTPN1PTPRCPTPN2PTPRBPTPN6 | |
| SCHEMBL8773534 | 0.78 | MAOB (0.64) | PTPN1PTPRCPTPN2PTPRBPTPN6 | |
| SCHEMBL2865421 | 0.76 | RXRA (0.56) | PTPN1PTPRCPTPN2PTPRBPTPN6 | |
| SCHEMBL23474598 | 0.74 | GAA (0.58) | PTPN1PTPRCPTPN2PTPRBPTPN6 | |
| SCHEMBL5511945 | 0.74 | PTPRC (0.54) | PTPN1PTPRCPTPN2PTPRBPTPN6 | |
| SCHEMBL3457914 | 0.74 | PTPRC (0.54) | PTPN1PTPRCPTPN2PTPRBPTPN6 | |
| SCHEMBL5507599 | 0.74 | PTPN1 (0.57) | PTPN1PTPRCPTPN2PTPRBPTPN6 | |
| SCHEMBL2873573 | 0.72 | MAOB (0.69) | PTPN1PTPRCPTPN2PTPRBPTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577555-B1 | Derivatives of carboxylic acids | CIBA GEIGY AG (CH) | 1997-11-05 | — | — | EP | claimed |