Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773563 | 0.83 | RXRA (0.46) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8773537 | 0.80 | PTPN1 (0.52) | MAOBRXRARXRBRXRGLIPE | |
| SCHEMBL11083620 | 0.77 | MAPT (0.52) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL31556117 | 0.77 | HPGD (0.61) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL7606605 | 0.77 | RXRA (0.65) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL8773569 | 0.76 | MAOB (0.54) | MAPTMAPK1ALDH1A1SMN1; SMN2APP | |
| SCHEMBL12908047 | 0.74 | MAPT (0.52) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL11091137 | 0.74 | APP (0.69) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL31556121 | 0.74 | APP (0.54) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL28931748 | 0.74 | MAPT (0.52) | HTR1AADRA1DADRA1AADRA1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577555-B1 | Derivatives of carboxylic acids | CIBA GEIGY AG (CH) | 1997-11-05 | — | — | EP | claimed |