Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034451 | 0.79 | POLB (0.51) | ALDH1A1MAPTLCKEPHX1HTT | |
| SCHEMBL28784043 | 0.78 | POLB (0.56) | ALDH1A1MAPTEPHX1HTTEPHX2 | |
| SCHEMBL29409425 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTLCKEPHX1HTT | |
| SCHEMBL4352883 | 0.75 | EPHX2 (0.56) | ALDH1A1MAPTEPHX1HTTEPHX2 | |
| SCHEMBL8601461 | 0.74 | EPHX2 (0.58) | ALDH1A1MAPTEPHX1HTTEPHX2 | |
| SCHEMBL8598214 | 0.74 | EPHX2 (0.58) | ALDH1A1MAPTEPHX1HTTEPHX2 | |
| SCHEMBL8601081 | 0.74 | EPHX2 (0.58) | ALDH1A1MAPTEPHX1HTTEPHX2 | |
| SCHEMBL8603519 | 0.74 | EPHX2 (0.58) | ALDH1A1MAPTEPHX1HTTEPHX2 | |
| SCHEMBL8602428 | 0.74 | EPHX2 (0.58) | ALDH1A1MAPTEPHX1HTTEPHX2 | |
| SCHEMBL4341280 | 0.73 | EPHX2 (0.57) | ALDH1A1EPHX1HTTEPHX2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609457-B1 | BENZENE DERIVATIVE | EISAI CO LTD (JP) | 1997-10-29 | — | — | EP | disclosed |
| US-5462958-A | Administering a cholesterol O-acyl transferase inhibitor | EISAI CO., LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0609457-A1 | BENZENE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |