Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363330 | 0.81 | ALDH1A1 (0.51) | POLBALDH1A1MAPTLCKHTT | |
| SCHEMBL17672416 | 0.80 | EPHX1 (0.57) | POLBALDH1A1HTTEPHX1NPSR1 | |
| SCHEMBL11219143 | 0.79 | LMNA (0.51) | POLBALDH1A1MAPTLCKHTT | |
| SCHEMBL8773655 | 0.79 | ALDH1A1 (0.56) | POLBALDH1A1MAPTLCKHTT | |
| SCHEMBL9800895 | 0.79 | LCK (0.61) | ALDH1A1LCKHTTEPHX1EPHX2 | |
| SCHEMBL9800902 | 0.79 | LCK (0.61) | ALDH1A1LCKHTTEPHX1EPHX2 | |
| SCHEMBL10362737 | 0.78 | EPHX1 (0.58) | POLBALDH1A1HTTEPHX1LMNA | |
| SCHEMBL9800918 | 0.78 | EPHX2 (0.55) | ALDH1A1HTTEPHX1EPHX2 | |
| SCHEMBL9800925 | 0.78 | EPHX1 (0.55) | POLBALDH1A1HTTEPHX1LMNA | |
| SCHEMBL8919046 | 0.78 | EPHX1 (0.51) | POLBALDH1A1HTTEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20050014833-A1 | Cyclic compound and ppar agonist | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1452521-A1 | CYCLIC COMPOUND AND PPAR AGONIST | Eisai Co., Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |
| EP-0609457-B1 | BENZENE DERIVATIVE | EISAI CO LTD (JP) | 1997-10-29 | — | — | EP | disclosed |
| US-5462958-A | Administering a cholesterol O-acyl transferase inhibitor | EISAI CO., LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0609457-A1 | BENZENE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014833-A1 | Cyclic compound and ppar agonist | PPARA, PPARG, PPARD | POLB 1978/4885ALDH1A1 1662/4885MAPT 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.