Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.62 |
| ▸ | CTSS | P25774 | 7/20 | 0.62 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778417 | 1.00 | CTSK (0.62) | CTSKCTSSCTSBCTSLATM | |
| SCHEMBL9125635 | 0.86 | CTSK (0.57) | CTSKCTSSCTSBCTSLATM | |
| SCHEMBL14673543 | 0.86 | CTSK (0.57) | CTSKCTSSCTSBCTSLATM | |
| SCHEMBL27730329 | 0.86 | CTSK (0.62) | CTSKCTSSCTSBCTSLATM | |
| SCHEMBL28108976 | 0.86 | CTSK (0.62) | CTSKCTSSCTSBCTSLATM | |
| SCHEMBL22042132 | 0.86 | CTSK (0.62) | CTSKCTSSCTSBCTSLATM | |
| SCHEMBL8885056 | 0.85 | CTSK (0.56) | CTSKCTSSCTSBCTSLATM | |
| SCHEMBL1886638 | 0.84 | KLK5 (0.57) | CTSKCTSSCTSBCTSLATM | |
| SCHEMBL9697661 | 0.83 | CTSS (0.54) | CTSKCTSSKLK5 | |
| SCHEMBL8882647 | 0.83 | CTSK (0.54) | CTSKCTSSCTSBCTSLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804410-A1 | METHOD OF PREPARING RETROVIRAL PROTEASE INHIBITOR INTERMEDIATES | G.D. SEARLE & CO. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022275-A1 | METHOD OF PREPARING RETROVIRAL PROTEASE INHIBITOR INTERMEDIATES | G.D. SEARLE & CO. (US) | 1996-07-25 | — | — | WO | disclosed |