SCHEMBL8773737

SCHEMBL8773737

CCCCC(=O)CCC(C)C=O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
KMT2A Q03164 1/20 0.41
CES1 P23141 2/20 0.39
CES2 O00748 1/20 0.39
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 2/20 0.37
TP53 P04637 1/20 0.37
TRPA1 O75762 1/20 0.36
DDAH1 O94760 1/20 0.36
GAPDH P04406 1/20 0.36
CTSK P43235 2/20 0.36
CA1 P00915 3/20 0.35
FAAH O00519 2/20 0.34
SLC15A1 P46059 1/20 0.34
IAPP P10997 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22289273 0.88 CES2 (0.35) MAPTKMT2ACES1CES2TSHR
SCHEMBL9301269 0.86 KMT2A (0.48) MAPTKMT2ACES1CES2TRPA1
SCHEMBL9316335 0.85 KMT2A (0.52) MAPTKMT2ACES1CES2TSHR
SCHEMBL6861160 0.81 TDP1 (0.39) CA1
SCHEMBL109369 0.79 KMT2A (0.46) MAPTKMT2ACES1CES2ALDH1A1
2-Methylpentanal SCHEMBL15789794 0.78 CES1 (0.39) MAPTCES1CES2TSHRSMN1; SMN2
SCHEMBL11318349 0.78 TDP1 (0.36) TSHRSMN1; SMN2CTSK
SCHEMBL8620850 0.77 MAPT (0.45) MAPTKMT2ACES1CES2ALDH1A1
SCHEMBL6292845 0.76 KMT2A (0.45) MAPTKMT2ACES1CES2TSHR
SCHEMBL3484833 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4212825-A Aldol condensation and hydrogenation process using a catalyst of nickel and cobalt together with zinc oxide and another metal of groups VIII, IIb, IIIa, IVa and Va of the periodic table BASF AKTIENGESELLSCHAFT (DE) 1980-07-15 US claimed
EP-0802904-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-10-29 EP disclosed
US-4239657-A CATALYST FOR ALDOL CONDENSATION AND HYDROGENATION BASF AKTIENGESELLSCHAFT (DE) 1980-12-16 US disclosed
US-4212825-A Aldol condensation and hydrogenation process using a catalyst of nickel and cobalt together with zinc oxide and another metal of groups VIII, IIb, IIIa, IVa and Va of the periodic table BASF AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
US-4049571-A SURFACE AFTERTREATMENT USING ZINC SALTS OF CARBOXYLIC ACIDS BASF AKTIENGESELLSCHAFT (DT) 1977-09-20 US disclosed