Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316335 | 0.94 | KMT2A (0.52) | KMT2AMAPTCES2CES1FAAH | |
| SCHEMBL8773737 | 0.86 | MAPT (0.41) | KMT2AMAPTCES2CES1FAAH | |
| SCHEMBL11318349 | 0.84 | TDP1 (0.36) | — | |
| SCHEMBL6292845 | 0.82 | KMT2A (0.45) | KMT2AMAPTCES2CES1FAAH | |
| SCHEMBL8080117 | 0.81 | — | — | |
| SCHEMBL13784898 | 0.81 | — | — | |
| SCHEMBL277790 | 0.81 | — | — | |
| SCHEMBL21853352 | 0.81 | KMT2A (0.48) | KMT2AMAPTCES2CES1FAAH | |
| SCHEMBL15054215 | 0.81 | ADH1B (0.44) | KMT2AMAPTCES2CES1FAAH | |
| SCHEMBL15544260 | 0.79 | KMT2A (0.56) | KMT2AMAPTCES2CES1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354768-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-11 | — | — | US | disclosed |