Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10466997 | 0.72 | SIRT2 (0.49) | KDM4EGAACYP3A4HPRT1HTT | |
| SCHEMBL3002 | 0.70 | ALDH1A1 (0.41) | KDM4EGAACYP3A4HPRT1POLB | |
| SCHEMBL395374 | 0.69 | GAA (0.33) | KDM4EGAACYP3A4PDPK1POLB | |
| SCHEMBL18398743 | 0.67 | IDO1 (0.55) | KDM4EHPRT1POLBPARP1HTT | |
| SCHEMBL3079936 | 0.62 | BCHE (0.40) | KDM4EGAACYP3A4PARP1HSD17B10 | |
| SCHEMBL555502 | 0.62 | CYP1A2 (0.44) | KDM4EGAACYP3A4PDPK1POLB | |
| SCHEMBL6244226 | 0.61 | HPRT1 (0.73) | KDM4ECYP3A4HPRT1POLBPARP1 | |
| SCHEMBL2557 | 0.61 | — | — | |
| SCHEMBL7579630 | 0.59 | MEN1 (0.44) | KDM4EGAAPDPK1PARP1HTT | |
| SCHEMBL18398744 | 0.58 | KDM4E (0.47) | KDM4EGAACYP3A4PDPK1HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804428-A1 | BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-11-05 | — | — | EP | claimed |