Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773819 | 0.85 | — | — | |
| SCHEMBL8773839 | 0.72 | ACHE (0.33) | — | |
| SCHEMBL8773850 | 0.66 | CYP3A4 (0.32) | — | |
| SCHEMBL8773861 | 0.64 | CYP3A4 (0.31) | TSHR | |
| SCHEMBL8773804 | 0.63 | TSHR (0.38) | TSHR | |
| SCHEMBL8773857 | 0.60 | TSHR (0.34) | TSHR | |
| SCHEMBL8773840 | 0.60 | TSHR (0.33) | TSHR | |
| SCHEMBL8773822 | 0.59 | TSHR (0.38) | TSHR | |
| 1,2-Dichlorobenzene SCHEMBL21634789 | 0.59 | TSHR (0.71) | TSHR | |
| 1,2-Dichlorobenzene SCHEMBL31146806 | 0.59 | TSHR (0.71) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470669-B1 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5164502-A | Fluorinating agents | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| US-5116982-A | Fluorination | DOWELANCO (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0470669-A2 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1992-02-12 | — | — | EP | disclosed |