SCHEMBL8773839

SCHEMBL8773839

F[B-](F)(F)F.F[n+]1c(Cl)cccc1C(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8773861 0.94 CYP3A4 (0.31)
SCHEMBL63583 0.80
SCHEMBL105038 0.72
SCHEMBL8773824 0.72 TSHR (0.30)
Nitrapyrin SCHEMBL9644896 0.69 ACHE (0.30) ACHE
SCHEMBL8773840 0.64 TSHR (0.33)
SCHEMBL17286403 0.63
SCHEMBL8773857 0.60 TSHR (0.34)
Trifluoromethanesulfonic Acid SCHEMBL63721 0.60 GPR3 (0.43) ACHE
SCHEMBL11485064 0.60 MAPT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470669-B1 Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines DOWELANCO (US) 1997-11-12 EP claimed
US-5164502-A Fluorinating agents DOWELANCO (US) 1992-11-17 US claimed
EP-0470669-A2 Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines DOWELANCO (US) 1992-02-12 EP claimed
EP-0470669-B1 Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines DOWELANCO (US) 1997-11-12 EP disclosed
US-5164502-A Fluorinating agents DOWELANCO (US) 1992-11-17 US disclosed
US-5116982-A Fluorination DOWELANCO (US) 1992-05-26 US disclosed
EP-0470669-A2 Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines DOWELANCO (US) 1992-02-12 EP disclosed