Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774247 | 0.81 | GPR3 (0.46) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| Bromide SCHEMBL3383748 | 0.78 | GPR3 (0.46) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| Fluoride Ion SCHEMBL3384407 | 0.78 | GPR3 (0.46) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL3385863 | 0.78 | GPR3 (0.46) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| Iodide SCHEMBL3382484 | 0.78 | GPR3 (0.46) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL3894356 | 0.72 | GPR3 (0.39) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL8159748 | 0.71 | GPR3 (0.41) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL8153895 | 0.71 | GPR3 (0.41) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL633764 | 0.67 | HTR2A (0.58) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL4632310 | 0.67 | ELANE (0.44) | ACHECHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476671-B1 | Homogeneous catalysts for olefin polymerization | DOW CHEMICAL CO (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0745617-A2 | Olefin polymerisation process | THE DOW CHEMICAL COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |
| US-5312938-A | Complexing an aminotitanium compound with an indene compound | THE DOW CHEMICAL COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-5194532-A | Complexes of titanium, indene derivatives and secondary amines | THE DOW CHEMICAL COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0476671-A2 | Homogeneous catalysts and olefin polymerization process | THE DOW CHEMICAL COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |