Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.41 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.41 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL3384407 | 0.94 | GPR3 (0.46) | GPR3HTR2AACHECHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL3385863 | 0.94 | GPR3 (0.46) | GPR3HTR2AACHECHRM2HTR1A | |
| Iodide SCHEMBL3382484 | 0.94 | GPR3 (0.46) | GPR3HTR2AACHECHRM2HTR1A | |
| SCHEMBL8774247 | 0.86 | GPR3 (0.46) | GPR3HTR2AACHECHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL8159748 | 0.80 | GPR3 (0.41) | GPR3HTR2AACHECHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL8153895 | 0.80 | GPR3 (0.41) | GPR3HTR2AACHECHRM2HTR1A | |
| SCHEMBL8774018 | 0.78 | ACHE (0.41) | GPR3HTR2AACHECHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL3894356 | 0.77 | GPR3 (0.39) | GPR3HTR2AACHECHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL4632310 | 0.75 | ELANE (0.44) | GPR3ACHECHRM2HTR1AADRA2A | |
| SCHEMBL29950614 | 0.73 | GPR3 (0.50) | GPR3HTR2AACHECHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709586-B2 | Olefin polymerization catalyst and olefin polymerization process using the same | DAELIM INDUSTRIAL CO., LTD. (KR) | 2010-05-04 | — | — | US | disclosed |
| US-20070142221-A1 | Olefin polymerization catalyst and olefin polymerization process using the same | DAELIM INDUSTRIAL CO., LTD. | 2007-06-21 | — | — | US | disclosed |