SCHEMBL8774032

SCHEMBL8774032

CCCCCCCCOc1ccc(-c2ccc(OCc3ccccc3)c(F)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.51
RARA P10276 1/20 0.51
FFAR1 O14842 4/20 0.49
PPARD Q03181 4/20 0.49
ERN1 O75460 1/20 0.47
LTA4H P09960 1/20 0.47
HRH3 Q9Y5N1 1/20 0.45
NR5A1 Q13285 1/20 0.44
FAAH O00519 6/20 0.43
MGLL Q99685 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9484875 0.95 FFAR1 (0.52) RARBRARAFFAR1PPARDERN1
SCHEMBL8773957 0.92 ERN1 (0.51) FFAR1PPARDERN1
SCHEMBL8773964 0.92 ERN1 (0.51) FFAR1PPARDERN1
SCHEMBL8774013 0.92 ERN1 (0.51) FFAR1PPARDERN1
SCHEMBL8773970 0.92 ERN1 (0.51) FFAR1PPARDERN1
SCHEMBL9152857 0.87 RARB (0.53) RARBRARALTA4HNR5A1FAAH
SCHEMBL10339089 0.87 RARB (0.53) RARBRARALTA4HNR5A1FAAH
SCHEMBL9223363 0.86 RARB (0.56) RARBRARAFFAR1PPARDERN1
SCHEMBL7788886 0.84 PTPN11 (0.53) RARBRARA
SCHEMBL7786753 0.84 PTPN11 (0.53) RARBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0496896-B1 CYCLOBUTANECARBOXYLIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME KANTO KAGAKU (JP) 1997-11-05 EP disclosed
US-5545747-A STABLE FERROELECTRIC LIQUID CRYSTALLINE COMPOUNDS KANTO KAGAKU KABUSHIKI KAISHA (JP) 1996-08-13 US disclosed
EP-0388141-B1 Ferroelectric liquid crystal device SHARP KK (JP) 1995-03-08 EP disclosed
US-5374373-A Liquid crystal mixture SHARP KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5182047-A FLUORINATED BIPHENYLDIOLE DERIVATIVES MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1993-01-26 US disclosed
EP-0368975-B1 FLUORINATED BIPHENYLDIOLE DERIVATIVES MERCK PATENT GmbH (DE) 1992-12-16 EP disclosed
EP-0496896-A1 CYCLOBUTANECARBOXYLIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME KANTO KAGAKU KABUSHIKI KAISHA (JP) 1992-08-05 EP disclosed
EP-0388141-A1 Ferroelectric liquid crystal device SHARP KABUSHIKI KAISHA (JP) 1990-09-19 EP disclosed
EP-0368975-A1 FLUORINATED BIPHENYLDIOLE DERIVATIVES. MERCK PATENT GMBH (DE) 1990-05-23 EP disclosed
WO-1989012039-A1 FLUORINATED BIPHENYLDIOLE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-12-14 WO disclosed