Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | RARB | P10826 | 4/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774032 | 0.95 | RARB (0.51) | FFAR1PPARDRARBRARAERN1 | |
| SCHEMBL8773970 | 0.92 | ERN1 (0.51) | FFAR1PPARDERN1PTPN11PTPN1 | |
| SCHEMBL8773957 | 0.92 | ERN1 (0.51) | FFAR1PPARDERN1PTPN11PTPN1 | |
| SCHEMBL8773964 | 0.92 | ERN1 (0.51) | FFAR1PPARDERN1PTPN11PTPN1 | |
| SCHEMBL8774013 | 0.92 | ERN1 (0.51) | FFAR1PPARDERN1PTPN11PTPN1 | |
| SCHEMBL9152857 | 0.87 | RARB (0.53) | RARBRARAPTPN11PTPN1PTPN6 | |
| SCHEMBL10339089 | 0.87 | RARB (0.53) | RARBRARAPTPN11PTPN1PTPN6 | |
| SCHEMBL7788886 | 0.87 | PTPN11 (0.53) | RARBRARAPTPN11PTPN1PTPN6 | |
| SCHEMBL7786753 | 0.87 | PTPN11 (0.53) | RARBRARAPTPN11PTPN1PTPN6 | |
| SCHEMBL8652239 | 0.85 | LOXL2 (0.45) | FFAR1PPARDERN1PTPN11PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182047-A | FLUORINATED BIPHENYLDIOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1993-01-26 | — | — | US | disclosed |
| EP-0368975-B1 | FLUORINATED BIPHENYLDIOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-12-16 | — | — | EP | disclosed |