Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773970 | 1.00 | ERN1 (0.51) | ERN1PTPN11PTPN1PTPN6C5AR1 | |
| SCHEMBL8773957 | 1.00 | ERN1 (0.51) | ERN1PTPN11PTPN1PTPN6C5AR1 | |
| SCHEMBL8773964 | 1.00 | ERN1 (0.51) | ERN1PTPN11PTPN1PTPN6C5AR1 | |
| SCHEMBL8774032 | 0.92 | RARB (0.51) | ERN1FFAR1PPARD | |
| SCHEMBL9484875 | 0.92 | FFAR1 (0.52) | ERN1PTPN11PTPN1PTPN6FFAR1 | |
| SCHEMBL8652239 | 0.89 | LOXL2 (0.45) | ERN1PTPN11PTPN1PTPN6C5AR1 | |
| SCHEMBL7786753 | 0.89 | PTPN11 (0.53) | PTPN11PTPN1PTPN6THRATHRB | |
| SCHEMBL7788886 | 0.89 | PTPN11 (0.53) | PTPN11PTPN1PTPN6THRATHRB | |
| SCHEMBL9223363 | 0.88 | RARB (0.56) | ERN1S1PR1ALOX5PSEN1FFAR1 | |
| SCHEMBL9484989 | 0.87 | THRA (0.53) | PTPN11PTPN1PTPN6THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496896-B1 | CYCLOBUTANECARBOXYLIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | KANTO KAGAKU (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5545747-A | STABLE FERROELECTRIC LIQUID CRYSTALLINE COMPOUNDS | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0496896-A1 | CYCLOBUTANECARBOXYLIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1992-08-05 | — | — | EP | disclosed |