Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADH1B | P00325 | 2/20 | 0.42 |
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | ADH7 | P40394 | 2/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL634153 | 1.00 | TSHR (0.47) | TSHRALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL15445 | 0.91 | — | — | |
| SCHEMBL17626634 | 0.91 | TSHR (0.53) | TSHRALDH1A1ADH1BADH1AADH7 | |
| Bromide SCHEMBL3468246 | 0.87 | — | — | |
| SCHEMBL21176007 | 0.87 | — | — | |
| SCHEMBL7184374 | 0.87 | — | — | |
| SCHEMBL6934656 | 0.87 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 | |
| Propane SCHEMBL20526066 | 0.87 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL6910828 | 0.87 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL4745526 | 0.87 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476671-B1 | Homogeneous catalysts for olefin polymerization | DOW CHEMICAL CO (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0745617-A2 | Olefin polymerisation process | THE DOW CHEMICAL COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |
| US-5312938-A | Complexing an aminotitanium compound with an indene compound | THE DOW CHEMICAL COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-5194532-A | Complexes of titanium, indene derivatives and secondary amines | THE DOW CHEMICAL COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0476671-A2 | Homogeneous catalysts and olefin polymerization process | THE DOW CHEMICAL COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |