Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADH1B | P00325 | 2/20 | 0.42 |
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | ADH7 | P40394 | 2/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL8774248 | 1.00 | TSHR (0.47) | TSHRALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL15445 | 0.91 | — | — | |
| SCHEMBL17626634 | 0.91 | TSHR (0.53) | TSHRALDH1A1ADH1BADH1AADH7 | |
| Bromide SCHEMBL3468246 | 0.87 | — | — | |
| SCHEMBL21176007 | 0.87 | — | — | |
| SCHEMBL7184374 | 0.87 | — | — | |
| SCHEMBL6934656 | 0.87 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 | |
| Propane SCHEMBL20526066 | 0.87 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL6910828 | 0.87 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL4745526 | 0.87 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829674-A | Composition for chemical conversion treatment of Zn-Al-Mg alloy-coated steel sheet, and Zn-Al-Mg alloy-coated steel sheet | POSCO公司 | 2022-07-29 | — | — | CN | claimed |
| US-10106638-B2 | Reduced emissions low density spray polyurethane foam | EVONIK DEGUSSA GMBH (DE) | 2018-10-23 | — | — | US | claimed |
| EP-2736937-A1 | REDUCED EMISSIONS LOW DENSITY SPRAY POLYURETHANE FOAM | Air Products and Chemicals, Inc. (US) | 2014-06-04 | — | — | EP | claimed |
| US-8513318-B2 | Method for producing a rigid polyurethane foam | TOSOH CORPORATION (JP) | 2013-08-20 | — | — | US | claimed |
| US-20130190415-A1 | Reduced Emissions Low Density Spray Polyurethane Foam | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-07-25 | — | — | US | claimed |
| WO-2013019488-A1 | REDUCED EMISSIONS LOW DENSITY SPRAY POLYURETHANE FOAM | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-02-07 | — | — | WO | claimed |
| US-8222311-B2 | Hydroxyalkylated polyalkylenepolyamine composition, method of producing the same and their use in polyurethanes | TOSOH CORPORATION (JP) | 2012-07-17 | — | — | US | claimed |
| EP-2196493-B1 | Catalyst composition for water blown, low density, rigid polyurethane foam | AIR PROD & CHEM (US) | 2012-02-22 | — | — | EP | claimed |
| US-7872055-B2 | Catalyst composition for water blown, low density, rigid polyurethane foam | Air Products and Chenicals, Inc. (US) | 2011-01-18 | — | — | US | claimed |
| US-20100152312-A1 | CATALYST COMPOSITION FOR WATER BLOWN, LOW DENSITY, RIGID POLYURETHANE FOAM | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2010-06-17 | — | — | US | claimed |
| US-20080004362-A1 | Hydroxyalkylated Polyalkylenepolyamine Composition, Method for Producing Same and Method for Producing Polyurethane Resin Using Such Hydroxyalkylated Polyalkylenepolyamine Composition | TOSOCH CORPORATION (JP) | 2008-01-03 | — | — | US | claimed |
| EP-1273604-B1 | Method for producing a rigid polyurethane foam | TOSOH CORP (JP) | 2007-06-13 | — | — | EP | claimed |
| US-20070021517-A1 | Method for producing a rigid polyurethane foam | TOSOH CORPORATION (JP) | 2007-01-25 | — | — | US | claimed |
| US-20040162360-A1 | Method for producing a rigid polyurethane foam | TOSOH CORPORATION (JP) | 2004-08-19 | — | — | US | claimed |
| US-6777456-B2 | REACTING POLYOL WITH POLYISOCYANATE IN PRESENCE OF AMINE CATALYST AND BLOWING AGENT, WHEREIN AS AMINE CATALYST, AMINE COMPOUND HAVING SUBSTITUENT SELECTED FROM HYDROXYL GROUP, PRIMARY AMINO GROUP AND SECONDARY AMINO GROUP IS USED | TOSOH CORPORATION (JP) | 2004-08-17 | — | — | US | claimed |
| US-20030083393-A1 | Method for producing a rigid polyurethane foam | TOSOH CORPORATION (JP) | 2003-05-01 | — | — | US | claimed |
| EP-1273604-A1 | Method for producing a rigid polyurethane foam | Tosoh Corporation (JP) | 2003-01-08 | — | — | EP | claimed |
| EP-0410467-B1 | Process for producing high resilience Polyurethane foam | TOSOH CORP (JP) | 1996-12-18 | — | — | EP | claimed |
| US-5104907-A | Amine type catalyst and water as blowing agent | TOSOH CORPORATION (JP) | 1992-04-14 | — | — | US | claimed |
| EP-0410467-A2 | Process for producing high resilience Polyurethane foam | Tosoh Corporation (JP) | 1991-01-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004362-A1 | Hydroxyalkylated Polyalkylenepolyamine Composition, Method for Producing Same and Method for Producing Polyurethane Resin Using Such Hydroxyalkylated Polyalkylenepolyamine Composition | SRM, HRH3, HNMT | TSHR 3753/4885ALDH1A1 1371/4885ADH1B 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.