Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.44 |
| ▸ | MMP2 | P08253 | 8/20 | 0.42 |
| ▸ | MMP3 | P08254 | 8/20 | 0.42 |
| ▸ | MMP9 | P14780 | 8/20 | 0.42 |
| ▸ | MMP13 | P45452 | 8/20 | 0.42 |
| ▸ | MMP1 | P03956 | 5/20 | 0.42 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873568 | 0.94 | GPR139 (0.44) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL876635 | 0.91 | MMP2 (0.52) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL877971 | 0.91 | MMP2 (0.52) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL874812 | 0.91 | GPR139 (0.46) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL874766 | 0.91 | GPR139 (0.39) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL877097 | 0.89 | EIF4EBP1 (0.39) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL877478 | 0.88 | GPR139 (0.50) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL877140 | 0.85 | MMP2 (0.51) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL877531 | 0.85 | MMP2 (0.51) | GPR139MMP2MMP3MMP9MMP13 | |
| SCHEMBL877199 | 0.84 | MMP2 (0.44) | GPR139MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |