Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 6/20 | 0.35 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774422 | 1.00 | PANK3 (0.35) | PANK3USP25SPHK1PCSK9KDM5A | |
| SCHEMBL8774341 | 0.96 | SPHK1 (0.39) | SPHK1DRD2SLC6A2HTR2AHTR2C | |
| SCHEMBL8774331 | 0.96 | SPHK1 (0.39) | SPHK1DRD2SLC6A2HTR2AHTR2C | |
| SCHEMBL8774794 | 0.92 | PANK3 (0.36) | PANK3USP25KDM5AKDM4CDRD2 | |
| SCHEMBL8774803 | 0.92 | PANK3 (0.36) | PANK3USP25KDM5AKDM4CDRD2 | |
| SCHEMBL8774873 | 0.87 | SPHK1 (0.49) | SPHK1 | |
| SCHEMBL8774869 | 0.87 | SPHK1 (0.49) | SPHK1 | |
| SCHEMBL9161057 | 0.87 | SPHK1 (0.35) | PANK3USP25SPHK1PCSK9SKP2 | |
| SCHEMBL9161069 | 0.87 | SPHK1 (0.35) | PANK3USP25SPHK1PCSK9SKP2 | |
| SCHEMBL8774094 | 0.87 | PANK3 (0.38) | PANK3USP25KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |