Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774024 | 0.94 | TP53 (0.35) | MAPTALDH1A1 | |
| SCHEMBL8774123 | 0.84 | PPARG (0.35) | PPARGCA12CA1CA2CA9 | |
| SCHEMBL4868026 | 0.76 | NAAA (0.37) | MAPTALDH1A1EPHX2CYP1A2 | |
| SCHEMBL11340566 | 0.71 | LMNA (0.40) | MAPTALDH1A1 | |
| SCHEMBL4868042 | 0.69 | MAPT (0.36) | MAPTALDH1A1EPHX2CYP1A2 | |
| SCHEMBL1297286 | 0.69 | PPARG (0.41) | MAPTPPARGALDH1A1EPHX2 | |
| SCHEMBL1297434 | 0.68 | PPM1B (0.45) | MAPTPPARGCA12CA1CA2 | |
| SCHEMBL1297073 | 0.67 | NAAA (0.47) | PPARGEPHX2 | |
| SCHEMBL1297515 | 0.67 | NAAA (0.47) | PPARGEPHX2 | |
| SCHEMBL1298058 | 0.67 | NAAA (0.47) | PPARGEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496896-B1 | CYCLOBUTANECARBOXYLIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | KANTO KAGAKU (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5545747-A | STABLE FERROELECTRIC LIQUID CRYSTALLINE COMPOUNDS | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0496896-A1 | CYCLOBUTANECARBOXYLIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1992-08-05 | — | — | EP | disclosed |