Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 7/20 | 0.50 |
| ▸ | KCNJ11 | Q14654 | 7/20 | 0.50 |
| ▸ | ABCC8 | Q09428 | 5/20 | 0.50 |
| ▸ | KCNJ8 | Q15842 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774807 | 1.00 | ABCC9 (0.50) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL9551254 | 0.86 | ABCC9 (0.55) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL9463611 | 0.86 | ABCC9 (0.55) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL6647586 | 0.84 | ABCC9 (0.62) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL2497201 | 0.84 | ABCC9 (0.62) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL11156357 | 0.83 | RAB9A (0.57) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL11162938 | 0.82 | ABCC9 (0.55) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL11152102 | 0.81 | ABCC9 (0.57) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL11157789 | 0.81 | ABCC9 (0.51) | ABCC9KCNJ11ABCC8KCNJ8KMT2A | |
| SCHEMBL11168464 | 0.81 | ABCC9 (0.60) | ABCC9KCNJ11ABCC8KCNJ8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655057-B1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS | UPJOHN CO (US) | 1997-09-17 | — | — | EP | claimed |
| EP-0655057-B1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS | UPJOHN CO (US) | 1997-09-17 | — | — | EP | disclosed |