Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390872 | 0.87 | DPP4 (1.00) | DPP4 | |
| SCHEMBL389654 | 0.87 | DPP4 (1.00) | DPP4 | |
| Trelagliptin SCHEMBL175726 | 0.86 | DPP4 (1.00) | DPP4CYP1A2CYP3A4CYP2D6 | |
| Trelagliptin SCHEMBL175727 | 0.86 | DPP4 (1.00) | DPP4CYP1A2CYP3A4CYP2D6 | |
| Trelagliptin SCHEMBL29349599 | 0.86 | DPP4 (1.00) | DPP4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27964065 | 0.84 | DPP4 (0.86) | DPP4CYP1A2CYP3A4CYP2D6 | |
| Benzoic Acid SCHEMBL20474742 | 0.81 | DPP4 (0.86) | DPP4CYP3A4 | |
| Trelagliptin SCHEMBL29364762 | 0.81 | DPP4 (1.00) | DPP4CYP1A2CYP3A4CYP2D6 | |
| Trelagliptin SCHEMBL28390472 | 0.81 | DPP4 (1.00) | DPP4CYP1A2CYP3A4CYP2D6 | |
| Trelagliptin SCHEMBL19534887 | 0.81 | DPP4 (1.00) | DPP4CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129878-A1 | TABLET | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2012-05-24 | — | — | US | disclosed |
| US-20120129878-A1 | TABLET | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129878-A1 | TABLET | AQP1, PNN, PFN1 | DPP4 6/4885CYP1A2 2362/4885CYP3A4 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.