Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774468 | 0.92 | FFAR1 (0.40) | FFAR1EGLN1EGLN3HSD17B10 | |
| SCHEMBL8774475 | 0.91 | FFAR1 (0.40) | FFAR1EGLN1EGLN3ALDH1A1TP53 | |
| SCHEMBL8774403 | 0.89 | FFAR1 (0.38) | FFAR1EGLN1EGLN3ACACBFFAR4 | |
| SCHEMBL8774295 | 0.87 | FFAR1 (0.44) | FFAR1ACACBFFAR4 | |
| SCHEMBL8774994 | 0.84 | FFAR1 (0.42) | FFAR1ACACBRAB9AFFAR4NPC1 | |
| SCHEMBL8978893 | 0.81 | FFAR1 (0.43) | FFAR1ACACBFFAR4 | |
| SCHEMBL8774821 | 0.80 | FFAR1 (0.43) | FFAR1RAB9AFFAR4NPC1TP53 | |
| SCHEMBL8774374 | 0.78 | FFAR1 (0.42) | FFAR1FFAR4ALDH1A1TP53HSD17B10 | |
| SCHEMBL9156722 | 0.78 | FFAR1 (0.41) | FFAR1ACACBRAB9AALDH1A1 | |
| SCHEMBL8774302 | 0.77 | HSD17B10 (0.43) | FFAR1FFAR4ALDH1A1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |