Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774475 | 0.96 | FFAR1 (0.40) | FFAR1EGLN1EGLN3PTPN11PTPRO | |
| SCHEMBL8774969 | 0.92 | FFAR1 (0.42) | FFAR1EGLN1EGLN3HSD17B10 | |
| SCHEMBL8774821 | 0.88 | FFAR1 (0.43) | FFAR1PTPN11PTPROTSHRHSD17B10 | |
| SCHEMBL8774403 | 0.87 | FFAR1 (0.38) | FFAR1EGLN1EGLN3 | |
| SCHEMBL8774912 | 0.85 | TSHR (0.43) | FFAR1PTPN11PTPROCTRCTSHR | |
| SCHEMBL8774374 | 0.84 | FFAR1 (0.42) | FFAR1PTPN11PTPROTSHRHSD17B10 | |
| SCHEMBL8774302 | 0.83 | HSD17B10 (0.43) | FFAR1PTPN11PTPROTSHRHSD17B10 | |
| SCHEMBL8979018 | 0.82 | HSD17B10 (0.41) | FFAR1PTPN11PTPROTSHRHSD17B10 | |
| SCHEMBL8774909 | 0.81 | HSD17B10 (0.48) | FFAR1TSHRHSD17B10MAPT | |
| SCHEMBL8774295 | 0.80 | FFAR1 (0.44) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |