Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 8/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.54 |
| ▸ | GABRP | O00591 | 3/20 | 0.43 |
| ▸ | GABRD | O14764 | 3/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.43 |
| ▸ | GABRE | P78334 | 3/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597438 | 0.98 | GABRA1 (0.52) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL22605562 | 0.88 | GABRA1 (0.51) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL11820041 | 0.79 | CNR1 (0.54) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL21272229 | 0.76 | CHRM1 (0.40) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL8532923 | 0.74 | NOS2 (0.38) | LMNATSHRHPGDKMT2AMEN1 | |
| SCHEMBL8532921 | 0.74 | NOS2 (0.38) | LMNATSHRHPGDKMT2AMEN1 | |
| SCHEMBL8726547 | 0.72 | GABRA1 (0.42) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL4701849 | 0.72 | NOS2 (0.38) | LMNATSHRHPGDKMT2AMEN1 | |
| SCHEMBL8537085 | 0.72 | NOS2 (0.38) | LMNATSHRHPGDKMT2AMEN1 | |
| SCHEMBL8537088 | 0.72 | NOS2 (0.38) | LMNATSHRHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |