SCHEMBL8775075

SCHEMBL8775075

CO[Si](CCc1ccc(CCNCCN)cc1)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.46
TAAR1 Q96RJ0 1/20 0.42
SLC2A1 P11166 1/20 0.39
MAOB P27338 2/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
CA4 P22748 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
ANPEP P15144 1/20 0.38
ERAP2 Q6P179 1/20 0.38
HTT P42858 1/20 0.37
CA5A P35218 1/20 0.37
CA14 Q9ULX7 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL720704 0.89 CHRM2 (0.46) SIGMAR1TAAR1CA12CA1CA2
SCHEMBL10477511 0.88 CA12 (0.39) TAAR1CA12CA1CA2CA9
SCHEMBL9480077 0.87 TAAR1 (0.47) SIGMAR1TAAR1SLC2A1MAOBMEN1
SCHEMBL10382875 0.82 CHRM2 (0.44) SIGMAR1TAAR1CA12CA1CA2
SCHEMBL12190393 0.82 TAAR1 (0.61) TAAR1MAOBMEN1KMT2AALDH1A1
SCHEMBL14273169 0.82 MAPT (0.46) TAAR1MAOBSMN1; SMN2GAAMEN1
SCHEMBL4290489 0.81 TAAR1 (0.66) SIGMAR1TAAR1MAOBCA12CA1
SCHEMBL139733 0.80 TAAR1 (0.43) SIGMAR1TAAR1MAOBSMN1; SMN2
SCHEMBL37761 0.79 SIGMAR1 (0.42) SIGMAR1GAA
SCHEMBL9660429 0.78 TAAR1 (0.45) TAAR1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0462570-B1 Magnetic recording medium MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1997-11-19 EP claimed
US-5219652-A Back coat layer including spherical particles which have been surface-treated for lubricity MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1993-06-15 US claimed
US-11818849-B1 Increasing adhesion of metal-organic interfaces by silane vapor treatment YIELD ENGINEERING SYSTEMS, INC. (US) 2023-11-14 US disclosed