SCHEMBL9660429

SCHEMBL9660429

CO[Si](CCc1ccc(CN)cc1)(OC)OC

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.45
MAOB P27338 7/20 0.43
LOXL2 Q9Y4K0 5/20 0.41
HRH3 Q9Y5N1 1/20 0.41
LOX P28300 1/20 0.40
ABAT P80404 1/20 0.38
ST14 Q9Y5Y6 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139733 0.89 TAAR1 (0.43) TAAR1MAOBKDM4E
SCHEMBL12190393 0.88 TAAR1 (0.61) TAAR1MAOBLOXL2KDM4EATM
SCHEMBL4291669 0.87 TAAR1 (0.41) TAAR1MAOBKDM4EATM
SCHEMBL9658109 0.85 TAAR1 (0.47) TAAR1MAOBLOXL2LOX
SCHEMBL8955746 0.83 CYP19A1 (0.53) TAAR1MAOBLOXL2KDM4EATM
SCHEMBL27094924 0.83 MAOB (0.48) TAAR1MAOBHRH3
Ethylenediamine SCHEMBL8775078 0.82 TAAR1 (0.55) TAAR1MAOBKDM4EATM
SCHEMBL8961179 0.82 LOXL2 (0.40) TAAR1MAOBLOXL2HRH3LOX
SCHEMBL5485070 0.81 TAAR1 (0.46) TAAR1MAOB
SCHEMBL11648990 0.81 TAAR1 (0.46) TAAR1MAOBHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185512-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-07-02 US disclosed
US-8822891-B2 Sheet heater and image fixing device including the sheet heater Konica Minolta, Inc. (JP) 2014-09-02 US disclosed
US-20140061181-A1 SHEET HEATER AND IMAGE FIXING DEVICE INCLUDING THE SHEET HEATER Konica Minolta, Inc. (JP) 2014-03-06 US disclosed
US-20130021546-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2013-01-24 US disclosed
US-5130402-A Chip resistant coatings of polyurethanes SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-07-14 US disclosed
US-4863831-A Photosensitive lithographic plate requiring no dampening water having a gelatin primer layer FUJI PHOTO FILM CO., LTD. (JP) 1989-09-05 US disclosed
US-4861698-A HARDENED GELATIN, SILICONE RUBBER FUJI PHOTO FILM CO., LTD. (JP) 1989-08-29 US disclosed
US-4769308-A Dry presensitized plate with photosensitive layer containing organotin FUJI PHOTO FILM CO., LTD. (JP) 1988-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130021546-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME ZKSCAN2, L1CAM, SDC2 TAAR1 3101/4885MAOB 3890/4885LOXL2 1504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.