Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11674043 | 0.98 | LCK (0.40) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL8775422 | 0.95 | CA2 (0.39) | LCKPPARDZDHHC20ZDHHC2CA1 | |
| SCHEMBL3108908 | 0.88 | CHRNB2 (0.31) | — | |
| SCHEMBL28789066 | 0.83 | LCK (0.44) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL18613642 | 0.83 | LCK (0.44) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL7290715 | 0.80 | TDP1 (0.31) | — | |
| SCHEMBL33997 | 0.80 | TDP1 (0.31) | — | |
| SCHEMBL28931846 | 0.80 | CA2 (0.38) | LCKPPARDZDHHC20ZDHHC2CA1 | |
| Hydrochloric Acid SCHEMBL153917 | 0.79 | TDP1 (0.31) | — | |
| Bromide SCHEMBL3232025 | 0.79 | TDP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606742-B1 | Bile acid sequestrant | ROHM & HAAS (US) | 1997-11-19 | — | — | EP | claimed |
| US-5451397-A | Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels | ROHM AND HAAS COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| EP-0606742-A1 | Bile acid sequestrant | ROHM AND HAAS COMPANY (US) | 1994-07-20 | — | — | EP | claimed |
| US-4020192-A | AMINO ALKYL AMIDE ACRYLIC POLYMER | FUJI XEROX CO., LTD. (JA) | 1977-04-26 | — | — | US | claimed |
| EP-0606742-B1 | Bile acid sequestrant | ROHM & HAAS (US) | 1997-11-19 | — | — | EP | disclosed |
| US-5451397-A | Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels | ROHM AND HAAS COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0606742-A1 | Bile acid sequestrant | ROHM AND HAAS COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |
| US-5300288-A | Acrylic amide polymers | ROHM AND HAAS COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0459632-A1 | Composition and method for controlling cholesterol | ROHM AND HAAS COMPANY (US) | 1991-12-04 | — | — | EP | disclosed |
| US-4520210-A | ALKYLATION IN WATER SOLUBLE KETONE THEN SEPARATION | BASF AKTIENGESELLSCHAFT (DE) | 1985-05-28 | — | — | US | disclosed |
| US-4020192-A | AMINO ALKYL AMIDE ACRYLIC POLYMER | FUJI XEROX CO., LTD. (JA) | 1977-04-26 | — | — | US | disclosed |