Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20471957 | 0.85 | KDM4E (0.43) | KDM4ETSHRGAAALDH1A1L3MBTL1 | |
| SCHEMBL8464596 | 0.84 | ALDH1A1 (0.55) | KDM4ETSHRGAAALDH1A1L3MBTL1 | |
| SCHEMBL20802641 | 0.84 | KDM4E (0.52) | KDM4ETSHRGAAALDH1A1L3MBTL1 | |
| SCHEMBL15922818 | 0.82 | KDM4E (0.51) | KDM4ETSHRGAAALDH1A1L3MBTL1 | |
| SCHEMBL8168167 | 0.81 | TSHR (0.68) | KDM4ETSHRGAAALDH1A1L3MBTL1 | |
| SCHEMBL31007085 | 0.81 | KDM4E (0.53) | KDM4EGAAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL3315009 | 0.81 | KDM4E (0.74) | KDM4ETSHRGAAALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8164468 | 0.79 | TSHR (0.66) | KDM4ETSHRGAAALDH1A1L3MBTL1 | |
| SCHEMBL20802720 | 0.79 | KDM4E (0.54) | KDM4ETSHRGAAALDH1A1L3MBTL1 | |
| SCHEMBL8774940 | 0.78 | KDM4E (0.47) | KDM4ETSHRGAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641831-B1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA LTD (JP) | 1997-11-12 | — | — | EP | disclosed |
| US-5464922-A | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0641831-A1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA, Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |