Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463263 | 0.86 | HSD17B2 (0.48) | KDM4ETSHRKMT2ACA12CA1 | |
| SCHEMBL15528629 | 0.84 | KDM4E (0.65) | KDM4ETSHRKMT2ACYP3A4L3MBTL1 | |
| SCHEMBL31171420 | 0.79 | TSHR (0.60) | KDM4ETSHRKMT2ACA12CA1 | |
| SCHEMBL31171418 | 0.79 | TSHR (0.60) | KDM4ETSHRKMT2ACA12CA1 | |
| SCHEMBL8775313 | 0.78 | KDM4E (0.53) | KDM4ETSHRKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL25428188 | 0.78 | KMT2A (0.46) | KDM4ETSHRKMT2ACA12CA1 | |
| SCHEMBL668867 | 0.78 | TSHR (0.54) | KDM4ETSHRKMT2ACYP3A4L3MBTL1 | |
| SCHEMBL9379667 | 0.77 | ALDH1A1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23458268 | 0.76 | POLB (0.40) | KDM4ERAB9AL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL7760951 | 0.75 | KMT2A (0.44) | TSHRRAB9AKMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641831-B1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA LTD (JP) | 1997-11-12 | — | — | EP | disclosed |
| US-5464922-A | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0641831-A1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA, Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |