Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.70 |
| ▸ | HTR3A | P46098 | 2/20 | 0.70 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.70 |
| ▸ | HTR3B | O95264 | 1/20 | 0.70 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.70 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23220843 | 0.88 | KMT2A (0.61) | ADRB1SIGMAR1HTR3AHTR3EHTR3B | |
| SCHEMBL23220824 | 0.88 | KMT2A (0.61) | ADRB1SIGMAR1HTR3AHTR3EHTR3B | |
| SCHEMBL149502 | 0.88 | KMT2A (0.61) | ADRB1SIGMAR1HTR3AHTR3EHTR3B | |
| SCHEMBL25645045 | 0.86 | ADRB1 (0.67) | ADRB1SIGMAR1HTR3AHTR3EHTR3B | |
| Ammonia Solution, Strong SCHEMBL28971896 | 0.86 | KMT2A (0.59) | ADRB1SIGMAR1HTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL27862880 | 0.86 | KMT2A (0.59) | ADRB1SIGMAR1HTR3AHTR3EHTR3B | |
| SCHEMBL17431870 | 0.86 | ADRB1 (0.95) | ADRB1SIGMAR1HTR3AHTR3EHTR3B | |
| Phenylpiperazine SCHEMBL29135595 | 0.83 | ADRB1 (1.00) | ADRB1SIGMAR1HTR3AHTR3EHTR3B | |
| Phenylpiperazine SCHEMBL55125 | 0.83 | ADRB1 (1.00) | ADRB1SIGMAR1HTR3AHTR3EHTR3B | |
| Phenylpiperazine SCHEMBL24889 | 0.83 | ADRB1 (1.00) | ADRB1SIGMAR1HTR3AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804441-A1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM PLC (GB) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022296-A1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-07-25 | — | — | WO | disclosed |