SCHEMBL149502

SCHEMBL149502

CN1CCN(c2ccccc2)CC1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
MAPT P10636 3/20 0.61
ADRA2C P18825 2/20 0.61
GAA P10253 2/20 0.61
ALDH1A1 P00352 2/20 0.61
KDM4E B2RXH2 1/20 0.61
GFER P55789 1/20 0.61
PTK2B Q14289 1/20 0.61
ESR2 Q92731 1/20 0.61
SIGMAR1 Q99720 2/20 0.61
DRD2 P14416 2/20 0.61
CHRNA7 P36544 2/20 0.59
HTR3A P46098 2/20 0.59
KCNH2 Q12809 1/20 0.57
RAD52 P43351 1/20 0.56
MAPK1 P28482 2/20 0.56
CYP3A4 P08684 1/20 0.56
ALOX15 P16050 1/20 0.56
CHRNB2 P17787 1/20 0.56
NFKB1 P19838 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23220843 1.00 KMT2A (0.61) KMT2AMAPTADRA2CGAAALDH1A1
SCHEMBL23220824 1.00 KMT2A (0.61) KMT2AMAPTADRA2CGAAALDH1A1
Hydrochloric Acid SCHEMBL27862880 0.98 KMT2A (0.59) KMT2AMAPTADRA2CGAAALDH1A1
Ammonia Solution, Strong SCHEMBL28971896 0.98 KMT2A (0.59) KMT2AMAPTADRA2CGAAALDH1A1
SCHEMBL9976438 0.91 CHKA (0.61) KMT2AMAPTADRA2CGAAALDH1A1
SCHEMBL17982868 0.89 KMT2A (0.52) KMT2AMAPTADRA2CGAAALDH1A1
Methylpiperazine SCHEMBL8775333 0.88 ADRB1 (0.70) KMT2AMAPTADRA2CGAAALDH1A1
SCHEMBL30108226 0.87 MELK (0.60) KMT2AMAPTADRA2CGAAALDH1A1
SCHEMBL576814 0.87 LMNA (0.67) KMT2AMAPTGAAALDH1A1SIGMAR1
SCHEMBL164538 0.87 LMNA (0.67) KMT2AMAPTGAAALDH1A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651897-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS Syntis Bio, Inc. (US) 2025-11-26 EP claimed
CN-119505231-A Copper-containing polymer, preparation thereof and application thereof in intracellular delivery of functional protein 华东师范大学 2025-02-25 CN claimed
EP-4416146-A1 SUBSTITUTED 1H-PYRAZOLO [4,3-C] QUINOLINES, METHODS OF PREPARATION, AND USE THEREOF Lomond Therapeutics, Inc. (US) 2024-08-21 EP claimed
US-20240261411-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS SYNTIS BIO, INC. 2024-08-08 US claimed
WO-2024155958-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS SYNTIS BIO, INC. (US) 2024-07-25 WO claimed
US-20230416258-A1 BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF CHINA PHARMACEUTICAL UNIVERSITY (CN) 2023-12-28 US claimed
EP-4242210-A1 NEW BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF China Pharmaceutical University (CN) 2023-09-13 EP claimed
WO-2023064133-A1 SUBSTITUTED 1H-PYRAZOLO [4,3-c] QUINOLINES, METHODS OF PREPARATION, AND USE THEREOF LOMOND THERAPEUTICS, INC. (US) 2023-04-20 WO claimed
WO-2023041071-A1 EGFR INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF 山东新时代药业有限公司 2023-03-23 WO claimed
CN-115108999-A Phenyl piperazine quinazoline compound or pharmaceutically acceptable salt thereof, preparation method and application 暨南大学 2022-09-27 CN claimed
EP-0764641-A1 NOVEL 4,5-DISUBSTITUTED PYRIMIDINE DERIVATIVE AND HERBICIDE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-03-26 EP claimed
EP-0644887-A1 PROCESS FOR THE PREPARATION OF CLAVULANIC ACID. SMITHKLINE BEECHAM PLC (GB) 1995-03-29 EP claimed
US-5378690-A Treatment of angiotensin induced hypertension SANKYO COMPANY, LIMITED (JP) 1995-01-03 US claimed
CN-1095069-A Novel process for the preparation and/or purification of clavulanic acid or pharmaceutically acceptable salts or esters thereof SMITHKLINE BEECHAM PLC (GB) 1994-11-16 CN claimed
EP-0274259-B1 New renin-inhibitory oligopeptides, their preparaton and their use SANKYO CO (JP) 1994-02-16 EP claimed
WO-1993025557-A1 PROCESS FOR THE PREPARATION OF CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 1993-12-23 WO claimed
EP-0274259-A2 New renin-inhibitory oligopeptides, their preparaton and their use Sankyo Company Limited (JP) 1988-07-13 EP claimed
EP-0226636-A1 NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS. BOEHRINGER MANNHEIM GMBH (DE) 1987-07-01 EP claimed
WO-1987000521-A2 NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS BOEHRINGER MANNHEIM GMBH (DE) 1987-01-29 WO claimed
US-4107437-A SEDATIVES, ANTIARRHYTHMIA AGENTS PARCOR (FR) 1978-08-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240261411-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS FABP2, SLC10A2, FABP6 KMT2A 2930/4885MAPT 4404/4885ADRA2C 3860/4885
US-20230416258-A1 BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF GABRA4, GABRA1, GABRA5 KMT2A 2078/4885MAPT 2953/4885ADRA2C 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.