Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28377249 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CES2CES1FAAHMEN1 | |
| SCHEMBL8775139 | 0.98 | CES2 (0.43) | ALDH1A1CES2CES1FAAHMEN1 | |
| SCHEMBL27350149 | 0.98 | CES2 (0.43) | ALDH1A1CES2CES1FAAHMEN1 | |
| SCHEMBL27436232 | 0.94 | ALDH1A1 (0.48) | ALDH1A1CES2CES1FAAHMEN1 | |
| SCHEMBL2501493 | 0.94 | ALDH1A1 (0.48) | ALDH1A1CES2CES1FAAHMEN1 | |
| SCHEMBL33996 | 0.86 | ALDH1A1 (0.37) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL151388 | 0.86 | ALDH1A1 (0.37) | ALDH1A1CES2CES1TSHR | |
| Hydrochloric Acid SCHEMBL5665875 | 0.84 | ALDH1A1 (0.35) | ALDH1A1CES2CES1TSHR | |
| Hydrochloric Acid SCHEMBL14237669 | 0.84 | ALDH1A1 (0.35) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL9321835 | 0.82 | FNTA (0.55) | ALDH1A1CES2CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606742-B1 | Bile acid sequestrant | ROHM & HAAS (US) | 1997-11-19 | — | — | EP | claimed |
| US-5451397-A | Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels | ROHM AND HAAS COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| EP-0606742-A1 | Bile acid sequestrant | ROHM AND HAAS COMPANY (US) | 1994-07-20 | — | — | EP | claimed |
| EP-0606742-B1 | Bile acid sequestrant | ROHM & HAAS (US) | 1997-11-19 | — | — | EP | disclosed |
| US-5451397-A | Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels | ROHM AND HAAS COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0606742-A1 | Bile acid sequestrant | ROHM AND HAAS COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |