Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636165 | 0.89 | NQO1 (0.48) | NQO1TSHRTDP1TP53CYP3A4 | |
| SCHEMBL146623 | 0.86 | NQO1 (0.50) | NQO1TSHRTDP1TP53CYP3A4 | |
| SCHEMBL8775498 | 0.80 | AHR (0.39) | TSHRCYP3A4AHRLTA4H | |
| SCHEMBL1637881 | 0.80 | NQO1 (0.33) | NQO1 | |
| SCHEMBL1637687 | 0.76 | NQO1 (0.44) | NQO1TSHRTDP1TP53CYP3A4 | |
| SCHEMBL8629428 | 0.74 | ESR1 (0.42) | NQO1CYP3A4ESR1AHRMAPT | |
| SCHEMBL1683212 | 0.72 | NQO1 (0.65) | NQO1TSHRTDP1TP53CYP3A4 | |
| SCHEMBL2302755 | 0.72 | NQO1 (0.38) | NQO1TSHRTDP1TP53CYP3A4 | |
| SCHEMBL28826013 | 0.71 | LTA4H (0.39) | LTA4HMAPTMEN1KMT2ANPC1 | |
| SCHEMBL20240843 | 0.71 | THRB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560724-B1 | Benzoyl substituted phosphabicycloalcanes and their sulphides as photoinitiators | CIBA GEIGY AG (CH) | 1997-09-24 | — | — | EP | disclosed |
| US-5399782-A | Addition polymerization, paints | CIBA-GEIGY CORPORATION (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0560724-A1 | Benzoyl substituted phosphabicycloalcanes and their sulphides as photoinitiators | CIBA-GEIGY AG (CH) | 1993-09-15 | — | — | EP | disclosed |