Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 7/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 7/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960976 | 0.98 | CKS1B (0.37) | CKS1BSKP2GLO1TOP2ANR1H2 | |
| SCHEMBL3941509 | 0.98 | CKS1B (0.37) | CKS1BSKP2GLO1TOP2ANR1H2 | |
| SCHEMBL93351 | 0.98 | CKS1B (0.37) | CKS1BSKP2GLO1TOP2ANR1H2 | |
| SCHEMBL29026619 | 0.96 | CKS1B (0.36) | CKS1BSKP2GLO1TOP2ANR1H2 | |
| SCHEMBL3964610 | 0.96 | CKS1B (0.36) | CKS1BSKP2GLO1TOP2ANR1H2 | |
| SCHEMBL30479688 | 0.96 | CKS1B (0.36) | CKS1BSKP2GLO1TOP2ANR1H2 | |
| SCHEMBL2424416 | 0.96 | CKS1B (0.36) | CKS1BSKP2GLO1TOP2ANR1H2 | |
| SCHEMBL769956 | 0.96 | CKS1B (0.36) | CKS1BSKP2GLO1TOP2ANR1H2 | |
| Dipyridyl SCHEMBL17766514 | 0.90 | GLO1 (0.35) | CKS1BSKP2GLO1TOP2ANR1H2 | |
| SCHEMBL8140844 | 0.82 | CKS1B (0.38) | CKS1BSKP2GLO1TOP2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807254-A1 | LUMINESCENT PROBES FOR PROTEIN DETECTION | TRUSTEES OF BOSTON UNIVERSITY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1997020213-A1 | LUMINESCENT PROBES FOR PROTEIN DETECTION | TRUSTEES OF BOSTON UNIVERSITY (US) | 1997-06-05 | — | — | WO | disclosed |