SCHEMBL8775865

SCHEMBL8775865

CCC(Cc1ccccc1)(C(=O)c1ccc(N2CCCC2)cc1)N(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
NPC1 O15118 5/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
RAB9A P51151 4/20 0.48
ALDH1A1 P00352 2/20 0.48
TP53 P04637 2/20 0.48
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
STAT1 P42224 1/20 0.48
HSD17B10 Q99714 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
KDM4E B2RXH2 1/20 0.46
NR4A1 P22736 1/20 0.46
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CNR2 P34972 2/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8899012 0.99 NPC1 (0.47) MAPTNPC1SMN1; SMN2RAB9AALDH1A1
SCHEMBL28131034 0.91 SMN1; SMN2 (0.48) MAPTNPC1SMN1; SMN2RAB9AALDH1A1
SCHEMBL3397043 0.91 SMN1; SMN2 (0.48) MAPTNPC1SMN1; SMN2RAB9AALDH1A1
SCHEMBL22722496 0.91 NPC1 (0.50) MAPTNPC1SMN1; SMN2RAB9ATP53
SCHEMBL35868 0.91 SMN1; SMN2 (0.48) MAPTNPC1SMN1; SMN2RAB9AALDH1A1
SCHEMBL28990186 0.91 SMN1; SMN2 (0.48) MAPTNPC1SMN1; SMN2RAB9AALDH1A1
SCHEMBL18905112 0.91 USP2 (0.41) MAPTNPC1SMN1; SMN2RAB9AALDH1A1
SCHEMBL22722520 0.91 KMT2A (0.54) MAPTNPC1SMN1; SMN2RAB9AHPGD
SCHEMBL4473427 0.90 ALDH1A1 (0.51) ALDH1A1TSHRHSD17B10MEN1KMT2A
Propane SCHEMBL27565501 0.90 SMN1; SMN2 (0.47) MAPTNPC1SMN1; SMN2RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0485334-B1 Photopolymerizable compositions TOKYO OHKA KOGYO CO LTD (JP) 1997-11-26 EP disclosed
US-5645974-A PHOTOPOLYMERIZATION INITIATOR COMPRISING BENZOYLAMINOBENZYLALKANE AND PHENYLDIALKOXYACETOPHENONE TOKYO OHKA KOGYO, K.K. (JP) 1997-07-08 US disclosed
US-5541038-A FOR THICK FILM PRINTING PLATES, MIXTURE OF PHOTOINITIATORS CIBA-GEIGY CORPORATION (US) 1996-07-30 US disclosed
EP-0485334-A2 Photopolymerizable compositions TOKYO OHKA KOGYO CO., LTD. (JP) 1992-05-13 EP disclosed