SCHEMBL4473427

SCHEMBL4473427

CCC(Cc1ccccc1)(C(=O)c1ccc(N2CCNCC2)cc1)N(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
USP2 O75604 1/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CETP P11597 2/20 0.42
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
ADRB1 P08588 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
ESRRG P62508 6/20 0.40
ESRRB O95718 5/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPKAPK2 P49137 3/20 0.40
KCNH2 Q12809 1/20 0.40
HTR6 P50406 1/20 0.40
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL17652252 0.97 ALDH1A1 (0.48) ALDH1A1USP2TSHRHSD17B10CETP
SCHEMBL2704646 0.94 ALDH1A1 (0.45) ALDH1A1USP2TSHRHSD17B10HTR3E
SCHEMBL23152941 0.90 MAPKAPK2 (0.50) ALDH1A1USP2TSHRHSD17B10CETP
SCHEMBL18910226 0.90 ADRB1 (0.48) ALDH1A1USP2TSHRHSD17B10ADRB1
SCHEMBL8775865 0.90 MAPT (0.48) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL17269404 0.89 HPGD (0.44) ALDH1A1USP2TSHRHSD17B10SIGMAR1
SCHEMBL19601159 0.89 LMNA (0.43) ALDH1A1USP2TSHRHSD17B10MEN1
SCHEMBL8899012 0.89 NPC1 (0.47) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL18910121 0.88 ALDH1A1 (0.50) ALDH1A1USP2TSHRHSD17B10HTR3E
SCHEMBL22722496 0.88 NPC1 (0.50) USP2MEN1KMT2AHTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10961405-B2 Fluorine-containing acetophenone derivative, fluroine based additive, curable composition including same, and cured product thereof DIC CORPORATION (JP) 2021-03-30 US disclosed
WO-2019198489-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, INSULATING MATERIAL, RESIN MATERIAL FOR SOLDER RESISTS AND RESIST MEMBER DIC株式会社 2019-10-17 WO disclosed
EP-2379512-B1 TRI-FUNCTIONAL UV-ABSORBING COMPOUNDS AND USE THEREOF NOVARTIS AG (CH) 2017-03-29 EP disclosed
US-8674089-B2 Michael addition reaction product and active energy ray-curable composition DIC CORPORATION (JP) 2014-03-18 US disclosed
US-8674089-B2 Michael addition reaction product and active energy ray-curable composition DIC CORPORATION (JP) 2014-03-18 US disclosed
EP-1812414-B1 PIPERAZINO BASED PHOTOINITIATORS SUN CHEMICAL LTD (GB) 2012-12-26 EP disclosed
US-8324256-B2 Tri-functional UV-absorbing compounds and use thereof NOVARTIS AG (CH) 2012-12-04 US disclosed
US-8324256-B2 Tri-functional UV-absorbing compounds and use thereof NOVARTIS AG (CH) 2012-12-04 US disclosed
US-20120190846-A1 MICHAEL ADDITION REACTION PRODUCT AND ACTIVE ENERGY RAY-CURABLE COMPOSITION DIC CORPORATION. (JP) 2012-07-26 US disclosed
US-20120190846-A1 MICHAEL ADDITION REACTION PRODUCT AND ACTIVE ENERGY RAY-CURABLE COMPOSITION DIC CORPORATION. (JP) 2012-07-26 US disclosed
WO-2010078001-A1 TRI-FUNCTIONAL UV-ABSORBING COMPOUNDS AND USE THEREOF NOVARTIS AG (CH) 2010-07-08 WO disclosed
US-20100168359-A1 TRI-FUNCTIONAL UV-ABSORBING COMPOUNDS AND USE THEREOF ALCON INC. (CH) 2010-07-01 US disclosed
US-20100168359-A1 TRI-FUNCTIONAL UV-ABSORBING COMPOUNDS AND USE THEREOF ALCON INC. (CH) 2010-07-01 US disclosed
US-7612122-B2 Piperazino based photoinitiators SUN CHEMICAL CORPORATION (US) 2009-11-03 US disclosed
US-7612122-B2 Piperazino based photoinitiators SUN CHEMICAL CORPORATION (US) 2009-11-03 US disclosed
US-7612122-B2 Piperazino based photoinitiators SUN CHEMICAL CORPORATION (US) 2009-11-03 US disclosed
US-20080045620-A1 Piperazino Based Photoinitiators SUN CHEMICAL CORPORATION (US) 2008-02-21 US disclosed
US-20080045620-A1 Piperazino Based Photoinitiators SUN CHEMICAL CORPORATION (US) 2008-02-21 US disclosed
US-20080045620-A1 Piperazino Based Photoinitiators SUN CHEMICAL CORPORATION (US) 2008-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100168359-A1 TRI-FUNCTIONAL UV-ABSORBING COMPOUNDS AND USE THEREOF UACA, TCOF1, TTPA ALDH1A1 992/4885USP2 615/4885TSHR 2855/4885
US-20080045620-A1 Piperazino Based Photoinitiators H1-3, H1-0, H1-2 ALDH1A1 1937/4885USP2 2452/4885TSHR 2061/4885
US-20120190846-A1 MICHAEL ADDITION REACTION PRODUCT AND ACTIVE ENERGY RAY-CURABLE COMPOSITION PARP14, TIPARP, PARP16 ALDH1A1 590/4885USP2 3914/4885TSHR 4224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.