Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 4/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775846 | 0.83 | CYP19A1 (0.46) | CYP19A1KIF11KCNA5TSHRKMT2A | |
| SCHEMBL6980412 | 0.77 | CES2 (0.44) | KIF11TSHRKMT2AMEN1 | |
| SCHEMBL8775806 | 0.71 | KCNA5 (0.52) | CYP19A1KIF11KCNA5TSHRKMT2A | |
| SCHEMBL11632766 | 0.71 | KCNA5 (0.51) | CYP19A1KCNA5CYP3A4KDM4EPOLB | |
| SCHEMBL11630182 | 0.70 | CYP3A4 (0.57) | CYP19A1KIF11KCNA5TSHRKMT2A | |
| SCHEMBL7068828 | 0.70 | CYP19A1 (0.57) | CYP19A1KIF11KCNA5TSHRKMT2A | |
| SCHEMBL13577 | 0.70 | CYP19A1 (0.57) | CYP19A1KIF11KCNA5TSHRKMT2A | |
| SCHEMBL29387897 | 0.70 | CYP19A1 (0.57) | CYP19A1KIF11KCNA5TSHRKMT2A | |
| SCHEMBL1380025 | 0.70 | KCNA5 (0.57) | CYP19A1KCNA5CYP3A4CYP3A5KDM4E | |
| SCHEMBL11468203 | 0.69 | KCNA5 (0.49) | CYP19A1KCNA5CYP3A4CYP3A5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |