Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775878 | 1.00 | TBXAS1 (0.71) | TBXAS1EPHX2SMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL8775786 | 1.00 | TBXAS1 (0.71) | TBXAS1EPHX2SMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL8775886 | 0.98 | TBXAS1 (0.68) | TBXAS1EPHX2SMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL9030394 | 0.88 | TBXAS1 (0.57) | TBXAS1EPHX2SMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL8699682 | 0.86 | TBXAS1 (0.60) | TBXAS1EPHX2SMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL5412370 | 0.84 | HRH1 (0.56) | TBXAS1CYP19A1HTR2AHRH1 | |
| SCHEMBL8775851 | 0.83 | TBXAS1 (0.66) | TBXAS1EPHX2SMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL5410942 | 0.82 | HRH1 (0.58) | TBXAS1LMNACYP19A1HTR2AHRH1 | |
| SCHEMBL14288463 | 0.82 | TBXAS1 (0.64) | TBXAS1EPHX2SMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL8775807 | 0.82 | TBXAS1 (0.82) | TBXAS1EPHX2SMN1; SMN2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |